Commission Implementing Decision (EU) 2018/945 of 22 June 2018 on the communicabl... (32018D0945) - Commission Implementing Decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions (Text with EEA relevance.) - Seite 61

At least one of the following three:

— Any person with fever

— Encephalitis

— Meningitis

Laboratory Criteria

Laboratory test for case confirmation

At least one of the following four:

— Isolation of WNV from blood or CSF

— Detection of WNV nucleic acid in blood or CSF

— WNV specific antibody response (IgM) in CSF

— WNV IgM high titre AND detection of WNV IgG, AND confirmation by neutralisation

Laboratory test for a probable case

WNV specific antibody response in serum

Laboratory results need to be interpreted according to flavivirus vaccination status

Epidemiological Criteria

At least one of the following two epidemiological links:

— Animal to human transmission (residing, having visited or having been exposed to mosquito bites in an area where WNV is endemic in horses or birds)

— Human to human transmission (vertical transmission, blood transfusion, transplants)

Case Classification

Possible case NA

Probable case

Any person meeting the clinical criteria AND with at least one of the following two:

— an epidemiological link

— a laboratory test for a probable case

Confirmed case

Any person meeting the laboratory criteria for case confirmation

Note:

Serological results should be interpreted according to previous exposure to other flaviviral infections and the flavivirus vaccination status. Confirmed cases in such situations should be validated by serum neutralization assay or other equivalent assays.

3.54. YELLOW FEVER

Clinical Criteria

Any person with fever

AND

At least one of the following two:

— Jaundice

— Generalised haemorrhage

Laboratory Criteria

At least one of the following five:

— Isolation of yellow fever virus from a clinical specimen

— Detection of yellow fever virus nucleic acid

— Detection of yellow fever antigen

— Yellow fever specific antibody response

— Demonstration of typical lesions in post mortem liver histopathology

Epidemiological Criteria

Travel in the last 1 week to a region where yellow fever cases are known or believed to have occurred

Case Classification

Possible case NA

Probable case

Any person meeting the clinical criteria with an epidemiological link

Confirmed case

Any person not recently vaccinated meeting the clinical and the laboratory criteria

In case of recent vaccination, a person with detection of wild-type yellow fever virus strain

Note:

3.55. ENTERITIS DUE TO YERSINIA ENTEROCOLITICA OR

YERSINIA PSEUDOTUBERCULOSIS

Clinical Criteria

Any person with at least one of the following five:

— Fever

— Diarrhoea

— Vomiting

— Abdominal pain (pseudoappendicitis)

— Rectal tenesmus